Endocrine Abstracts

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I have been the module leader for the Paediatric Endocrinology: exploring practice module for several years. Amongst those nurses who access or contribute to the course it is clear to see the wealth of knowledge, clinical expertise, enthusiasm for the subject area and professional commitment to delivering high quality nursing care to children, young people (CYP) and their families. Excellent examples of nursing care for CYP are presented in the assignments and every year I app...

Introduction: The age range at diagnosis, complexity of the syndrome and the sensitive and emotional nature of the issues involved in a diagnosis of Turner Syndrome (TS) present specific challenges for health professionals in sharing information with girls and their families. However little is known about the perceived information needs of parents and there has been no study of the views of girls with TS.Methods: A qualitative design was employed to expl...

A longstanding unsettled question is whether pancreatic β-cells originate from exocrine duct cells. We have now used a genetic labeling approach to fate map embryonic and adult pancreatic duct cells. We employed a BAC genomic clone containing the Hnf1b locus to generate a transgenic mouse line that expresses a hormone-inducible form of Cre in pancreatic ducts. We verified that in this model Cre is specifically expressed throughout the pancreatic duct epithelium, in...

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